Abstract #1407112: Assessment of the Thyroid Eye Disease Specific Graves’ Ophthalmopathy Quality of Life Questionnaire in Non-Inflammatory or Inactive Thyroid Eye Disease Patients

Patients (pts) with inactive/non-inflammatory thyroid eye disease (TED) previously reported similar negative quality of life as those active/inflammatory TED, using TED-specific Graves’ ophthalmopathy (GO-QOL) scores. Mean visual function and appearance scores 58.6 62.3, respectively, indicated significant impact. Here we examined specific areas affected by non-inflammatory TED. An online survey pts inactive assessed pt healthcare provider, was conducted in January 2020. Questions from the GO-QOL evaluated TED impact on activities (reading, watching TV, hobby or pastime, driving, walking outdoors, moving around house, bicycling), social interactions a 3-point scale: seriously very much/a little/not at all limited, not applicable. Caregiver assistance also evaluated. 100 (47, 47% female) were identified (mean age 45.2 ± 7.6 yrs). Outside individual symptoms, 28 (28%) that severe major feature On items, TV reading most affected, 86 (86%) 85 (85%) reporting some limitation, 32 (32%) serious limitation. 70 (70%) difficulty 59 (59%) limitation 57 (57%) hobbies pastimes. 58 (58%) hindrance to something they wanted do past week. 77 (77%) felt like their had changed because 11 (11%) much. 71 (71%) influence self-confidence 25 (25%) 72 (72%) appearing less often photos than before receiving caregiver (primarily partners) help for daily 41% (13/32) caregivers extremely involved communication pt’s provider. Among tasks necessitating aid caregiver, 69% (22/32) received grocery shopping cooking, 56% (18/32) transportation, 44% (14/32) household general healthcare. This analysis indicates continue feel after acute/inflammatory presentation fades many suffering limitations living activities. Pts report continues affect how interact people, almost third relying help.